|
MDIs and DPIs for Asthma and COPD, Sold in the US [February, 2003] |
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Drug Substance |
CFC/
non-CFC/ DPI |
Innovator/ Generic |
Drug
Product |
Manufacturer |
Approval
Date |
Source
(Imported or Domestic) |
Exported
to Other Parties? |
|
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Short-Acting Bronchodilators: |
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|
Albuterol |
CFC |
Innovator |
Proventil |
Schering
Plough |
|
Domestic |
No |
|
Ventolin |
GlaxoSmithKline |
|
Domestic |
Yes (Canada) |
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|
Generic |
Albuterol |
Andrx |
|
Domestic |
No |
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|
Albuterol |
Sidmak |
|
Domestic |
No |
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|
Albuterol |
Ivax |
|
Imported
(Ireland) |
No |
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|
Non-CFC |
Innovator |
Proventil
HFA |
3M |
8/15/1996 |
Domestic and
Imported |
No |
|
|
Ventolin HFA |
GlaxoSmithKline |
4/19/2001
(launched 2/02) |
Domestic |
Yes (UK) |
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|
Epinephrine
nitrate/HCl |
CFC |
Generic |
Epinephrine
Inhalation Aerosol |
Alpharma |
|
Domestic |
No |
|
Ipratropium
Bromide |
CFC |
Innovator |
Atrovent |
Boehringer
Ingelheim/ 3M |
|
Domestic |
No |
|
Metaproterenol
sulfate |
CFC |
Innovator |
Alupent |
Boehringer
Ingelheim/ 3M |
|
Domestic |
No |
|
Pirbuterol
acetate |
CFC |
Innovator |
Maxair
Autohaler |
3M |
|
Domestic |
No |
|
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Long-Acting Bronchodilators: |
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|
Formoterol
fumarate |
DPI |
Innovator |
Foradil
Aerolizer |
Novartis |
2/16/2001 |
Imported |
No |
|
Salmeterol
xinafoate |
CFC |
Innovator |
Serevent
Inhalation Aerosol |
GlaxoSmithKline |
|
Domestic |
Yes (Canada) |
|
DPI |
Innovator |
Serevent
Diskus |
GlaxoSmithKline |
9/19/1997 |
Imported
(UK) |
No |
|
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|
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Corticosteroids: |
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|
Beclomethasone
dipropionate |
Non-CFC |
Innovator |
Qvar 40 |
3M |
9/15/2000 |
Domestic and
Imported |
No |
|
Qvar 80 |
3M |
9/15/2000 |
Domestic and
Imported |
No |
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|
Budesonide |
DPI |
Innovator |
Pulmicort
DPI |
AstraZeneca |
6/24/1997 |
Imported |
No |
|
Flunisolide
hemihydrate |
CFC |
Innovator |
Aerobid |
Hoffman
LaRoche/ Forrest/ 3M |
|
Domestic |
No |
|
Fluticasone
propionate |
CFC |
Innovator |
Flovent
44mcg |
GlaxoSmithKline |
|
Domestic |
Yes (Canada) |
|
|
|
Flovent
110mcg |
GlaxoSmithKline |
|
Domestic |
Yes (Canada) |
|
|
Flovent
220mcg |
GlaxoSmithKline |
|
Domestic |
Yes (Canada) |
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|
DPI |
Innovator |
Flovent
Rotadisk |
GlaxoSmithKline |
11/7/1997 |
Imported |
No |
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Other Agents: |
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Cromolyn
Sodium |
CFC |
Innovator |
Intal |
Aventis |
|
Imported |
No |
|
Nedocromil
Sodium |
CFC |
Innovator |
Tilade |
Aventis |
|
Imported |
No |
|
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Combination Products: |
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|
Salmeterol
xinafoate/ fluticasone propionate |
DPI |
Innovator |
Advair
Diskus (100/50) |
GlaxoSmithKline |
8/24/2000 |
Imported |
No |
|
Advair
Diskus (250/50) |
GlaxoSmithKline |
8/24/2000 |
Imported |
No |
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|
Advair
Diskus (500/50) |
GlaxoSmithKline |
8/24/2000 |
Imported |
No |
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|
Albuterol
sulfate/ Ipratropium bromide |
CFC |
Innovator |
Combivent
MDI |
Boehringer
Ingelheim |
|
Domestic |
Yes (Canada) |