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Laboratory and analytical uses
Laboratory and analytical uses

Categories and examples of laboratory uses (not exhaustive list)

Reference

1. Research and development (e.g. pharmaceutical, pesticide, CFC

and HCFC substitutes)

1.1 Reaction solvent or reaction feedstock (e.g. Diels-Alder and Friedel-Craft Reactions, RuO3 oxidation, allelic side bromination, etc.)

2. Analytical uses and regulated applications (including quality control)

2.1 Reference

– Chemical (ODS monitoring, volatile organic compound (VOC) Detection, Equipment Calibration)

– Toxicant

– Product (adhesive bond strength, breathing filter test)

2.2 Extraction

– Pesticide and heavy metal detection (e.g. in food)

– Oil mist analysis

– Colour and food additive detection

– Oil detection in water and soil

2.3 Diluent

– Zinc, copper, cadmium detection in plants and food

– Microchemical methods to determine molecular weight or oxygen

– Measuring drug purity and residual determination

– Sterilization of lab equipment

2.4 Carrier (Inert)

– Forensic methods (e.g. fingerprinting)1

– Titration (cholesterol in eggs, drug chemical characteristics, “Iodine value”, e.g. in oils and chemical products)

– Analytical equipment (Spectroscopy (Infra-red, Ultra-violet, Nuclear Magnetic Resonance, fluorescence), chromatography (High-pressure liquid chromatography, gas chromatography, thin-layer chromatography)

2.5 Tracer

– Sanitary engineering

2.6 Miscellaneous (including testing)

– Ingredient in material for testing (e.g. asphalt, metal fatigue and fracturing)

– Separation media (separation of extraneous materials such as filth and insect excreta from stored food products)

3. Miscellaneous (including biochemical)

3.1 Laboratory method development

3.2 Sample preparation using solvent

3.3 Heat transfer medium

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Annex IV of the 7th MOP

adopted by decision VII/11

Categories of laboratory and analytical uses allowing the use of methyl bromide

Reference

(a) As a reference or standard:

(i) To calibrate equipment which uses methyl bromide

(ii) To monitor methyl bromide emission levels

(iii) To determine methyl bromide residue levels in goods, plants and commodities

(b) In a laboratory toxicological study

(c) To compare the efficacy of methyl bromide and its alternatives inside a laboratory;

(d) As a laboratory agent which is destroyed in a chemical reaction in the manner of feedstock

 

 

 

 

Decision XVIII/15

1 Forensic finger-printing is no longer exempted: https://ozone.unep.org/resources/categories-of-laboratory-and-analytical-uses-no-longer-exempted.

Laboratory and analytical uses

Categories of laboratory and analytical uses no longer exempted

Reference

1. Refrigeration and air-conditioning equipment used in laboratories, including refrigerated laboratory equipment such as ultra-centrifuges

2. Cleaning, reworking, repair, or rebuilding of electronic components or assemblies

3. Preservation of publications and archives

4. Sterilization of materials in a laboratory

Decision VII/11

5. Testing of oil, grease and total petroleum hydrocarbons in water

6. Testing of tar in road-paving materials

7. Forensic finger-printing

Decision XI/15

8. Testing of organic matter in coal

Decision XIX/18
Laboratory and analytical uses

Recalling decisions VII/11 and XXI/6, in which the Meeting of the Parties requested all parties to urge their national standards-setting organizations to identify and review their standards for laboratory and analytical procedures that mandate the use of Montreal Protocol controlled substances with a view to adopting, where possible, laboratory and analytical products and processes that do not use controlled substances,

Recalling also decisions VII/11, XI/15, XVIII/15 and XIX/18, by which the Meeting of the Parties eliminated specific uses from the global exemption for laboratory and analytical uses,

1. To extend the global laboratory and analytical-use exemption until 31 December 2021, under the conditions set out in annex II to the report of the Sixth Meeting of the Parties and decisions XV/8, XVI/16 and XVIII/15, for the controlled substances under the Montreal Protocol in all annexes and groups except Annex C, group 1;

2. To request the Technology and Economic Assessment Panel to report no later than 2018 on the development and availability of laboratory and analytical procedures that can be performed without using controlled substances under the Montreal Protocol;

3. To encourage parties to continue to investigate domestically the possibility of replacing ozone-depleting substances in laboratory and analytical uses and to share the resulting information;

Annex II : Conditions applied to exemption for laboratory and analytical uses

More information
Laboratory and analytical uses

Pursuant to Decision X/19 (4), the Secretariat is listing below decisions by the Parties on laboratory and analytical uses that should no longer be eligible for production and consumption of controlled ozone-depleting substances under the global exemption:

  • Uses excluded from the global essential-use exemption (Decision VII/11 (6)):
  1. Refrigeration and air-conditioning equipment used in laboratories, including refrigerated laboratory equipment such as ultra-centrifuges;
  2. Cleaning, reworking, repair, or rebuilding of electronic components or assemblies;
  3. Preservation of publications and archives; and
  4. Sterilization of materials in a laboratory;
  • Uses eliminated from the global exemption for laboratory and analytical uses (Decision XI/15)
  1. Testing of oil, grease and total petroleum hydrocarbons in water;
  2. Testing of tar in road-paving materials; and
  3. Forensic finger-printing.
  • Use eliminated from the global exemption for laboratory and analytical uses (Decision XIX/18)
  1. Testing of organic matter in coal
  • All uses of methyl bromide except those listed in decision XVIII/15 (see preamble of decision XXI/6)

Of relevance to the global exemption of laboratory and analytical uses are:

  • Conditions applied to exemption for laboratory and analytical uses (Annex II of the Report of the Sixth Meeting of the Parties)
  • Categories and examples of laboratory uses (Annex IV of the Report of the Seventh Meeting of the Parties)

Category of laboratory and analytical critical use to allow methyl bromide to be used (Decision XVIII/15(2))

Subject to the conditions applied to the exemption for laboratory and analytical uses contained in annex II to the report of the Sixth Meeting of the Parties, it was decided by the Parties to the Montreal Protocol at their Eighteenth Meeting to adopt a category of laboratory and analytical critical use to allow methyl bromide to be used:

“(a)      As a reference or standard:

(i)         To calibrate equipment which uses methyl bromide;
(ii)        To monitor methyl bromide emission levels;
(iii)       To determine methyl bromide residue levels in goods, plants and commodities;

    (b)        In laboratory toxicological studies;

    (c)        To compare the efficacy of methyl bromide and its alternatives inside a laboratory;

    (d)        As a laboratory agent which is destroyed in a chemical reaction in the manner of feedstock;”

    Laboratory and analytical uses

    Recalling decision XXVI/5, which extended the global laboratory and analytical-use exemption until 31 December 2021, under the conditions set out in annex II to the report of the Sixth Meeting of the Parties,

    Noting that Annex C, group I, substances (hydrochlorofluorocarbons) are currently not included in the global laboratory and analytical-use exemption,

    Noting the 2018 report by the Technology and Economic Assessment Panel, which notes that hydrochlorofluorocarbons will be required for laboratory and analytical uses after 2020,

    Taking into account the adjustment agreed on by parties in 2018 to permit essential-use exemptions for hydrochlorofluorocarbons,

    To include Annex C, group I, substances in the global laboratory and analytical-use exemption under the same conditions and on the same timeline as set forth in paragraph 1 of decision XXVI/5;

    More information
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    "The views of the authors presented in the scientific papers are their own. They do not represent the views or policy of the Ozone Secretariat or the Parties to the Vienna Convention and the Montreal Protocol. No official endorsement should be inferred. The Ozone Secretariat does not make any warranty or representation, either express or implied, with respect to the accuracy of the information contained therein and it does not assume any liability of any kind resulting from the use or reliance upon any information contained in those papers including links to websites".